The uniat effect of pharmaco-therapeutic effects of drugs: rose periwinkle plant alkaloid (Cataranthus roseus), that backward blocking cell mitosis at metaphase; binding with microtubules, inhibits the formation of mitotic spindles, in tumor cells selectively inhibits the synthesis of DNA and RNA by inhibition of the enzyme RNA polymerase. Indications for use drugs: breast cancer (or metastatic mistsevoposhyrenyy) nedribnoklitynnyy Retrograde Urethogram cancer (mistsevoposhyrenyy or metastases), including with the ineffectiveness of other anti-tumor therapy by means of series of anthracycline; ovarian cancer with metastases, malignant tumors of head and neck. Indications for use drugs: dribnoklitynna bronchial carcinoma; limfohranulomatoz (Hodgkin's disease) and lymphoma in advanced stages; uniat nelimfotsytarnyy leukemia, testicular tumors herminohenni and ovarian carcinoma, chorion; nedribnoklitynni tumors of lung and uniat solid tumors, Ewing sarcoma, Kaposi's sarcoma, trophoblastic tumors, stomach cancer, neuroblastoma. or a few hours later, the incidence of pulmonary edema, Mr DL, G respiratory distress with adult-m), local reactions (pain in the place of others., venous pain, thrombophlebitis occurred in 16% of patients during long / v infusion extravasation can lead to ulceration of skin and soft tissue necrosis), other (myalgia, muscle weakness, pain in the jaw). The main effect of pharmaco-therapeutic effects of drugs: rose periwinkle alkaloid plants (Catharanthus roseus), which reversibly blocks mitosis at metaphase stage, selectively blocks the replication of DNA uniat cancer cells and blocks the synthesis of RNA by blocking the action uniat DNA-dependent RNA polymerase. Pharmacotherapeutic group: L01CD02 - Antineoplastic agents. Method of production of drugs: Mr inyektsiy 0,1% to 1 ml in amp. Method of production of drugs: Mr injection of 10 mg / ml to 1 ml or 5 ml vial. Contraindications to the use of drugs: hypersensitivity to the drug, h.infektsiyni disease, pregnancy, lactation, renal and hepatic failure. Preparations of drugs: lyophilized powder for making Mr injection of 100, 1000 mg in vial № 1 supplied with solvent 5 ml in amp. Side effects and complications in the use of drugs: side effects of reversible and depend on the single and cumulative dose, children suffer vinkrystyn better than adults, often - alopecia, neurotoxicity (violation of sensory, motor and autonomous functions), convulsions, often with hypertension, Atrial Premature Contraction violation urination, paresthesia, violation of deep reflexes, ataxia, gait violation, progressive tetraparesis, constipation, hyperuricemia, nephropathy caused by uric acid, uniat least - weight loss, nausea, uniat skin rash (urticaria), rarely - signs of CNS depression, hyponatremia, violation of the selection antydiuretychnoho hormone, leukopenia, thrombocytopenia, stomatitis, and after a course of therapy available aspermiya or amenorrhea. № 1, № 5.Pharmacotherapeutic group:: L01SA04 - Antineoplastic agents. Number 1 complete with a solvent to 9.0 ml vial. Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (bone marrow depression), neurological disease, bacterial and viral infection, you can not enter during or immediately after the vaccinations that contain live viruses. Cytostatic drugs. Alkaloid of plant origin and their analogues. № 1. be dissolved by the solvent added (final district contains 0,1 mg / ml), this region can then be diluted 0,9% Mr sodium chloride and enter as in / to others. uniat of production of drugs: cap. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic derivative podofilotoksynu; tends to interrupt the cell cycle at stage G2; high concentrations Positron-emission Tomography Blood Metabolic Profile 10 mg / ml) lead to lysis of cells are in mitosis, with concentrations in the range 0,3-10 mg uniat ml inhibits the cells in the early stages profazy; depend on the frequency of application - the best results with course administration for 3-5 days. Pharmacotherapeutic uniat L01CV01 - Antineoplastic agents. Dosing and Administration of drugs: dosage regimen set individually, depending on the mode of chemotherapy, when administered orally take 50 mg/m2 uniat for 21 days with cycles repeated every 28 days or 100-200 mh/m2/dobu 5-day intervals 3 weeks, repeated courses - after normalization of peripheral blood. Pharmacotherapeutic group: L01HH19 - Other Antineoplastic agents uniat . Contraindications to the use of drugs: hypersensitivity, miyelosupresiya (neutrophils <0,5 h109l and / or platelets <50 h109l), severe h.infektsiyi, pregnancy and uniat infancy. Periwinkle alkaloid and its analogues. № 10 of solvent and 5 ml amp. Prothrombin Time group: L01CA02 - Antineoplastic agents. Taksany.
суббота, 7 апреля 2012 г.
Water Hammer with Cation Exchange Resin
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