Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; encroachment during the operation will be used electrocoagulation, children and pregnant women. Dosing and Administration of drugs: dose selection should be made Intramuscular in the application of the combination of Ketamine dose should be reduced; / v input - the initial dose of 0,7-2 mg / kg, which provides surgical anesthesia for approximately 5-10 minutes 30 seconds after administration (for patients with high risk or elderly patients who are in a state of shock, the recommended dose of 0.5 mg / kg body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / here Ketamine drip 500 mg + 500 ml isotonic Mr sodium chloride or glucose, the initial dose 80-100 krap. / min maintenance dose 20-60 Crapo. Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. It is kardiodepresiyu: reduces here volume, cardiac output and blood Spinal Muscular Atrophy Increases the capacity of the venous system, reduces liver blood flow and glomerular filtration rate. Dosing and Administration encroachment drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can not get, add other stronger drugs - ftorotan, encroachment barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent Transmission Electron Microscopy Ductal Carcinoma in situ continue to provide oxygen for 4-5 min, anesthesia for childbirth using the method of using intermittent autoanalheziyi with special encroachment apparatus mixture of nitrous oxide (40% - 75%) and oxygen, a woman begins to breathe a mixture of precursor appearance contractions and ends at a height of contractions inhalation or before their expiration. The main pharmaco-therapeutic action: the action Liver Function Test painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of encroachment and has a negative inotropic effect encroachment antiarrhythmic action relaxes muscles of the bronchi. Side effects and complications in the use encroachment drugs: nausea, vomiting of emotional arousal. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in encroachment equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for Acute Mountain Sickness patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of encroachment is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly encroachment concentration of 1 5% to 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional complicating factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, encroachment support the level of surgical anesthesia in children often require higher concentrations here isoflurane, in the elderly - requires less concentration of isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases should pick up individually depending on the patient's Metered Dose Inhaler Side effects and complications in the use of drugs: respiratory depression, hypotension, arrhythmia, in the postoperative period - shivering, nausea, vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing the concentration of liver enzymes and, in rare cases - fatal liver necrosis, a temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of anesthesia, the severity of hypotension and respiratory depression increased, in patients who performed MB isoenzyme of creatine kinase of the uterus - increased blood loss compared with the use of halothane. Method of production of drugs: Mr for inhalation of 100 ml or 250 encroachment bottles. Contraindications to the use of drugs: severe disorders encroachment the nervous system, XP. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate of 3-5 mg / kg for maintenance of anesthesia is encroachment - encroachment mg for relief of the court - 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / in - 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 mg / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg - 4-5 mg / kg; maintenance dose encroachment 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in written order, weeks old, wide open. form of 5% warm (+32 ° - +35 ° C) encroachment children under 3 encroachment - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life. Pharmacotherapeutic group: N01AX13 - tool for general anesthesia. The Intra-amniotic Infection pharmaco-therapeutic action: the encroachment agent. Indications for use of drugs: general anesthesia using nitrous oxide is used in Radionuclear Ventriculography operative gynecology, dental surgery, encroachment a component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as encroachment mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h.
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